Discoveries to Change Lives.
The worrying and increasing development of bacterial
resistance has led to the search of alternative substances
to antibiotics. One of them is the application of phage-encoded
lytic proteins, known as enzybiotics, on which our company is focused.



Telum Therapeutics SL is a global drug discovery biotechnology
company specializing in the use of Engineered Phage Lytic
Proteins as new antimicrobial products.
Numerous studies place the bacteriophages and, specially, their lytic enzymes, as one of the most promising alternatives to the traditional
antibiotics. For this reason, Telum Therapeutics is creating a broad bacteria and phage collection from anthropogenic and cave explorations to obtain new bacteriophages and lytic enzymes with potential antibacterial therapeutic purposes.
Telum’s mission in the field of antibiotic drug development is to give hope to patients suffering with drug resistant infections by developing new antimicrobial agents.
APEXp® under Trade secret protection
Advanced Phage Enzybiotics from exploration platform
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Sample collection

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APEXp® Under Trade Secret

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APEXp® Under Trade Secret

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APEXp® Under Trade Secret

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Protein Engineering

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High throughput screening

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Secondary Modifications

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Select Leading Candidates

APExTM
Advance Phage Enzybiotics from
exploration platform.
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Sample collection
Sample collection
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APEXp® Under Trade Secret
APEXp® Under Trade Secret
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APEXp® Under Trade Secret
APEXp® Under Trade Secret
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APEXp® Under Trade Secret
APEXp® Under Trade Secret
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Protein Engineering
Protein Engineering
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High throughput screening
High throughput screening
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Secondary Modifications
Secondary Modifications
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Select Leading Candidates
Select Leading Candidates
Telum Therapeutics Development Pipeline
Within our pipeline we have specific programs to treat serious multidrug-resistant Gram-negative infections caused by Enterobacteriaceae, Acinetobacter baumannii and Pseudomonas aeruginosa
Candidate Name
Target Pathogen
Indication
Rights
i
Therapies based on Engineered phage lytic enzymes (EPLEs) with enhanced antimicrobial activities aimed at combating and eliminating multi-resistant bacteria on the WHO list of priority pathogens.
Confidential
Acinetobacter baumannii, including CRAB
HABP/VABP
Fully-owned
Candidate Name
Confidential
Target Pathogen
Acinetobacter baumannii, including CRAB
Indication
HABP/VABP
Rights
i
Therapies based on Engineered phage lytic enzymes (EPLEs) with enhanced antimicrobial activities aimed at combating and eliminating multi-resistant bacteria on the WHO list of priority pathogens.
Fully-owned
IND enabling
Candidate Name
Target Pathogen
Indication
Rights
i
Therapies based on Engineered phage lytic enzymes (EPLEs) with enhanced antimicrobial activities aimed at combating and eliminating multi-resistant bacteria on the WHO list of priority pathogens.
Confidential
Staphylococcus aureus MRSA
Prosthetic Joint Infection (PJI) and cardiac implantable electronic device (CIED)
Fully-owned
Candidate Name
Confidential
Target Pathogen
Staphylococcus aureus MRSA
Indication
Prosthetic Joint Infection (PJI) and cardiac implantable electronic device (CIED)
Rights
i
Therapies based on Engineered phage lytic enzymes (EPLEs) with enhanced antimicrobial activities aimed at combating and eliminating multi-resistant bacteria on the WHO list of priority pathogens.
Fully-owned
Preclincial Phase
Candidate Name
Target Pathogen
Indication
Rights
i
Therapies based on Engineered phage lytic enzymes (EPLEs) with enhanced antimicrobial activities aimed at combating and eliminating multi-resistant bacteria on the WHO list of priority pathogens.
Confidential
Enterococcus faecium VRE
Nosocomial infections
Fully-owned
Candidate Name
Confidential
Target Pathogen
Enterococcus faecium VRE
Indication
Nosocomial infections
Rights
i
Therapies based on Engineered phage lytic enzymes (EPLEs) with enhanced antimicrobial activities aimed at combating and eliminating multi-resistant bacteria on the WHO list of priority pathogens.
Fully-owned
Preclinical Phase